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Best EPA-Registered Tick Repellents: DEET, Picaridin, and OLE
Compare the most effective EPA-registered tick repellents — DEET, picaridin, and oil of lemon eucalyptus — including how to choose for kids and pets.
The EPA registers repellents proven to deter biting insects, including ticks. The three most common active ingredients each have strengths, trade-offs, and use cases. This guide is general education only — check the product label and talk to your doctor or pediatrician for specifics.
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DEET
- Long history of use, effective against ticks at 20–30% concentration.
- Lasts several hours; higher concentrations last longer but plateau in effectiveness.
- Can damage some plastics and synthetic fabrics.
Picaridin
- Effective and odorless compared to DEET.
- Won't damage gear or fabrics.
- Often available as a 20% formulation.
Oil of Lemon Eucalyptus (OLE) / PMD
- Plant-derived option registered by the EPA.
- Not recommended for children under 3 (check label).
- Different from pure essential oils, which are not EPA-registered.
How to use repellents safely
- Apply to exposed skin and clothing, not under clothes.
- Avoid eyes, mouth, and cuts.
- For kids, spray on adult hands first, then apply.
- Always follow label instructions — including age restrictions.
Key takeaways
- Look for EPA-registered repellents — labels list active ingredient and concentration.
- DEET, picaridin, and OLE/PMD all repel ticks; choose based on duration and personal preference.
- Pair skin repellent with permethrin-treated clothing for the strongest protection.
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