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Diseases Linked to the Lone Star Tick

The Lone Star tick (Amblyomma americanum) is best known for its link to alpha-gal syndrome. But it can play a part in other illnesses too. The most common is ehrlichiosis. It is also linked to southern tick-associated rash illness (STARI) and, rarely, Heartland virus, Bourbon virus, and tularemia. The Lone Star tick is not thought to spread Lyme disease. This is an overview for learning. Only a licensed doctor can diagnose or treat any of these illnesses.

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The short version

  • Ehrlichiosis: a bacterial infection and the most common Lone Star tick illness. Antibiotics treat it when given early.
  • STARI: a rash that can follow a bite and grows over time. Its cause is not known, and it is not Lyme disease.
  • Alpha-gal syndrome: a delayed allergy to mammal meat that can start after bites.
  • Heartland & Bourbon viruses: rare viral illnesses. There is no specific antiviral treatment.
  • Tularemia: a bacterial illness that can spread by tick bites and in other ways.

Ehrlichiosis

It is the most often reported illness linked to the Lone Star tick. Early symptoms can include fever, headache, tiredness, and muscle aches. These often start within days to a couple of weeks of a bite. Get checked quickly, because antibiotics can treat it when it is caught early.

STARI (southern tick-associated rash illness)

STARI causes a rash around a Lone Star tick bite that grows, and it is sometimes shaped like a bull's-eye. Some people also have tiredness, headache, or muscle aches. Its exact cause is not known, and it is not Lyme disease. But a doctor should always check a rash after a tick bite.

Alpha-gal syndrome (AGS)

AGS is a delayed allergic reaction to alpha-gal, a sugar found in mammal meat. It can start after certain tick bites. Reactions tend to show up hours after eating red meat. See the alpha-gal guides for details.

Rarer concerns: Heartland virus, Bourbon virus, tularemia

Heartland and Bourbon viruses are rare illnesses linked to Lone Star tick bites. There is no specific antiviral treatment, so doctors treat the symptoms. Tularemia can spread through tick bites and in other ways. These illnesses are uncommon. But severe or lasting symptoms after a bite always need medical care.

The best protection is avoiding bites

All of these illnesses start the same way, with a tick bite. So the same steps protect against all of them: repellent, permethrin-treated clothing, staying out of tall grass and brush, and daily tick checks. Remove any attached tick quickly and the right way.

Common questions

Can the Lone Star tick give you Lyme disease?

No. The Lone Star tick is not thought to spread Lyme disease. Lyme is spread mainly by blacklegged (deer) ticks. A rash after a Lone Star tick bite may be STARI, which is a different illness. See a doctor about any rash.

What is the most common illness from a Lone Star tick?

Ehrlichiosis. It is the most often reported bacterial illness linked to the Lone Star tick. Antibiotics can treat it when given early, so get symptoms checked soon after a bite.

How soon do symptoms appear after a bite?

It depends on the illness. Some symptoms appear within days to a couple of weeks. An alpha-gal allergy can show up later, with reactions hours after eating red meat. Watch for symptoms for several weeks, and contact a doctor if any appear.

How do I lower my risk of all of these?

Prevent bites. Use EPA-registered repellent and treat clothing with permethrin. Stay out of tall grass and leaf litter, and check people and pets for ticks every day. Remove attached ticks right away with fine-tipped tweezers.

Sources

  1. 1.
  2. 2.
    Ehrlichiosis (opens in a new tab) · CDC

    Bacterial illness transmitted primarily by the Lone Star tick; treatable with prompt antibiotics.

  3. 3.
    Tickborne Diseases of the United States (STARI) (opens in a new tab) · CDC

    Southern Tick-Associated Rash Illness (STARI) follows some Lone Star tick bites; cause not established and it is not Lyme disease.

  4. 4.
    Heartland Virus (opens in a new tab) · CDC

    Rare virus associated with Lone Star tick bites; no specific antiviral treatment.

  5. 5.
    Alpha-gal Syndrome (opens in a new tab) · CDC

    What alpha-gal syndrome is, symptoms, and its association with tick bites.

  6. 6.

This guide is here to help you learn. It is not medical advice. If you have symptoms or questions, see a doctor. If someone has trouble breathing or a severe allergic reaction, call 911. Read our sources and disclaimer.